Research and analysis

Variants: distribution of case data, 21 January 2022

Updated 24 June 2022

Variants of concern or under investigation: data up to 19 January 2022

Surveillance overview

UK total distribution바카라 사이트 

Variant* Other names by which this variant may be known** Lineage Total confirmed (sequencing) and probable (genotyping) cases바카라 사이트¡ New cases since last update (data up to 12 January 2022)
Alpha VOC-20DEC-01 B.1.1.7 276,692 -1,667바카라 사이트 
Beta§ VOC-20DEC-02 B.1.351 1,071§ -37바카라 사이트 
Gamma VOC-21JAN-02 P.1 278 -6바카라 사이트 
Delta바카라 사이트  VOC-21APR-02 B.1.617.2 AY.1 AY.2 1,704,312바카라 사이트 â¶Ä  +736
VUI-21OCT-01*** VUI-21OCT-01 A.Y 4.2 121,111 +778
Omicron VOC-21NOV-01 B.1.1.529 762,615 +216,084
Zeta VUI-21JAN-01 P.2 57 0
VUI-21FEB-03 VUI-21FEB-03 B.1.525 (previously designated UK1188) 503 -10바카라 사이트 
VUI-21FEB-04 VUI-21FEB-04 B.1.1.318 396 +1
Theta VUI-21MAR-02 P.3 10 0
Kappa VUI-21APR-01 B.1.617.1 512 -9바카라 사이트 
VUI-21APR-03 VUI-21APR-03 B.1.617.3 17 -1바카라 사이트 
VUI-21MAY-02 VUI-21MAY-02 C.36.3 153 -5바카라 사이트 
Lambda VUI-21JUN-01 C.37 8 0
Mu§ VUI-21JUL-01 B.1.621 59§ 0

바카라 사이트  Negative numbers indicate variants that have been re-classified as Omicron or undetermined since the last update.

*Information pertaining to VUI-21MAR-01, B1.324.1 with E484K has been removed as this variant has been reclassified as provisionally extinct. Variants VUI-21FEB-01 (A.23.1 with E484K), and VOC-21FEB-02 (Alpha with E484K) are provisionally extinct (not detected for 12 weeks in the UK or in GISAID) therefore they will no longer be included in the publication from 12 November 2021. Variant VUI-21MAY-01, AV.1 has been removed as of 3 December 2021 as it has been classified as provisionally extinct.

**WHO naming has been included where available.

바카라 사이트 â¶Ä  Of which 742 had the K417N mutation.

바카라 사이트¡Confirmed individuals are confirmed COVID-19 cases with a validated sequencing result meeting the confirmed case definitions outlined in the sections below. Probable individuals are confirmed COVID-19 cases with a genotyping result where sequencing confirmation is awaited or not available. Published figures include genotyping assay data for England, using a combination of highly specific mutations as an indicator of a probable variant. Genotyping assay data is currently only available for Alpha, Beta (for specimen dates up to and including 30 June 2021), Delta and Gamma.

§Due to having identical genotyping profiles, since 1 July Beta and Mu cases identified by genotyping have been categorised as 바카라 사이트˜Beta or Mu바카라 사이트™. In addition to the above numbers, a further 17 바카라 사이트˜Beta or Mu바카라 사이트™ provisional genotyping cases have been identified.

***Confirmed VOC-21APR-02 with at least 2 VUI-21OCT-01 lineage defining positions called as alternate (variant) base and all other defining positions reported as N (unknown) or mixed bases.

Differences between a variant of concern and a variant under investigation

SARS-CoV-2 variants, if considered to have concerning epidemiological, immunological or pathogenic properties, are raised for formal investigation. At this point they are designated variant under investigation (VUI) with a year, month, and number. Following a risk assessment with the relevant expert committee, they may be designated variant of concern (VOC).

Changes in nomenclature

The previous variant names frequently include similar numbers with similar or repeating patterns. This makes referring to them verbally challenging. To overcome this challenge, a revised nomenclature has been agreed involving dropping the first 2 numbers of the year and replacing the 2-month numbers with a 3-letter abbreviation. This shortens the name and reduces the degree of repeated sequences of numbers. The table containing surveillance overview 바카라 사이트˜UK total distribution바카라 사이트™ contains a list of new variant names alongside previous or other names in use for VOCs and VUIs.

Alpha

Surveillance overview

This variant was first detected in the UK and was first sequenced in the UK in September 2020.

Total confirmed and probable cases
England 225,984
Northern Ireland 9,135
Scotland 29,130
Wales 12,443
Total cases 276,692

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 5 VOC-20DEC-01 lineage defining positions are called as alternate (variant) base and all other defining positions reported as N (unknown) or mixed bases
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Beta

Surveillance overview

This variant was first sequenced in the UK in December 2020.

Total confirmed and probable cases
England 957
Northern Ireland 9
Scotland 62
Wales 43
Total cases 1,071

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case where:
바카라 사이트¢ at least 4 VOC-20DEC-02 lineage defining positions are called as alternate (variant) base, and
바카라 사이트¢ all other defining positions reported as N (unknown) or mixed bases바카라 사이트¯
or
바카라 사이트¢ at least 5 of the 9 non-synonymous changes
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Gamma

Surveillance overview

This variant was first detected in the UK in February 2021.

Total confirmed and probable cases
England 253
Northern Ireland 0
Scotland 23
Wales 2
Total cases 278

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 5 lineage defining non-synonymous changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed bases
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Delta

Surveillance overview

Total confirmed and probable cases
England 1,387,049
Northern Ireland 93,120
Scotland 133,180
Wales 90,963
Total cases 1,704,312

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 4 variant defining changes called as alternate base
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

VUI-21OCT-01

Surveillance overview

Total confirmed and probable cases
England 91,973
Northern Ireland 737
Scotland 13,471
Wales 14,930
Total cases 121,111

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case that is confirmed VOC-21APR-02 with at least 2 VUI-21OCT-01 lineage defining positions called as alternate (variant) base and all other defining positions reported as N (unknown) or mixed bases.
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Omicron

Surveillance overview

Total confirmed and probable cases
England 650,253
Northern Ireland 37,416
Scotland 38,270
Wales 36,676
Total cases 762,615

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 10 lineage defining non-synonymous changes called as alternate base and no more than 7 defining positions called as wild-type
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR). Ìý

Zeta

Surveillance overview

This variant first sequenced in the UK in November 2020.

Total confirmed and probable cases
England 51
Northern Ireland 0
Scotland 5
Wales 1
Total cases 57

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* case confirmed as infected with VUI-21JAN-01 through whole genome sequencing (WGS) where:
바카라 사이트¢ results of all lineage defining non-synonymous changes called as alternate base
or
바카라 사이트¢ 6 of 7 non-synonymous changes called as alternate base, and
바카라 사이트¢ remaining position either N or mixed bases
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

VUI-21FEB-03

Surveillance overview

This variant was first detected in the UK in December 2020.

Total confirmed and probable cases
England 451
Northern Ireland 2
Scotland 40
Wales 10
Total cases 503

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 5 lineage defining non-synonymous changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed bases
Probable (genotyping) COVID-19* confirmed case with a genotyping result where sequencing confirmation is awaited or not available
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

VUI-21FEB-04

Surveillance overview

This variant was first detected in the UK (England).

Total confirmed and probable cases
England 345
Northern Ireland 40
Scotland 11
Wales 0
Total cases 396

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 5 lineage defining non-synonymous changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed base
or
바카라 사이트¢ at least 5 of the 9 non-synonymous changes
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Theta

Surveillance overview

Total confirmed and probable cases
England 7
Northern Ireland 0
Scotland 3
Wales 0
Total cases 10

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 7 variant defining changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed base
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Kappa

Surveillance overview

Total confirmed and probable cases
England 466
Northern Ireland 4
Scotland 27
Wales 15
Total cases 512

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 6** variant defining changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed base
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).
**Due to overlap with Delta sequences, the case definition of Kappa sequences was changed on 27 August 2021.

VUI-21APR-03

Surveillance overview

Total confirmed and probable cases
England 14
Northern Ireland 0
Scotland 0
Wales 3
Total cases 17

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19*바카라 사이트¯confirmed case with:
바카라 사이트¢ at least 8 variant defining changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed base
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

VUI-21MAY-02

Surveillance overview

Total confirmed and probable cases
England 143
Northern Ireland 2
Scotland 4
Wales 4
Total cases 153

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 5 variant defining changes called as alternate base, and
바카라 사이트¢ all other positions either N or mixed base.
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Lambda

Surveillance overview

Total confirmed and probable cases
England 8
Northern Ireland 0
Scotland 0
Wales 0
Total cases 8

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 5 VUI-21JUN-01 lineage defining positions are called as alternate (variant) base and all other defining positions reported as N (unknown) or mixed bases.
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).

Mu

Surveillance overview

Total confirmed and probable cases
England 53
Northern Ireland 2
Scotland 3
Wales 1
Total cases 59

Case definitions

Genomic match Criteria
Confirmed
(sequencing)
COVID-19* confirmed case with at least 5 VUI-21JUL-01 defining mutations called as alternate (variant) base and all other defining positions reported as N (unknown) or mixed bases.
*A confirmed COVID-19 case: a case where the individual is confirmed to be infected with SARS-CoV-2 by polymerase chain reaction (PCR).