Guidance

Hexavalent combination vaccine: programme guidance

Guidance for healthcare practitioners on the hexavalent vaccine programme, including its use in the selective neonatal hepatitis B programme, from 1 July 2025.

From:
UK Health Security Agency
Published
5 July 2017
Last updated
2 June 2025 바카라 사이트� See all updates

Applies to England

Documents

Hexavalent DTaP/IPV/Hib/HepB combination vaccine: information for healthcare practitioners

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Appendix A: the number of hepatitis-B containing vaccine doses for children 바카라 사이트� text version

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PDF, 290 KB, 1 page

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Details

All babies born on or after 1 August 2017 are eligible for the hexavalent vaccine, which includes hepatitis B (HepB), for their primary immunisations. From July 2025, the routine childhood immunisation schedule changed, and children born on or after 1 July 2024 will receive an additional hexavalent vaccine at 18 months of age. The selective neonatal hepatitis B pathway for children born to women with hepatitis B was also amended.

This guidance is aimed at healthcare practitioners involved in the programme and provides information about the hexavalent vaccines ( Vaxelis庐 and Infanrix hexa庐), including information on the changes, eligibility, scheduling and vaccine administration.聽Separate information for healthcare practitioner guidance, specifically covering the changes to the routine childhood schedule from 1 July 2025, is also available.

More information on the childhood changes to the vaccination schedule

Updates to this page

Published 5 July 2017
Last updated 2 June 2025 show all updates

  1. Updates made to the guidance for healthcare practitioners relating to the changes to the childhood schedule from 1 July 2025. Additional appendix A added.

  2. Added new slide set which includes all the changes to the childhood vaccination programme.

  3. Added updated guidance and training slide set.

  4. Updated information on incomplete or uncertain vaccination histories and stability of Vaxelis.

  5. Added updated information for healthcare practitioners and link to updated training slide set.

  6. Updated with revised infant PCV schedule and removed Hepatitis B pre-school booster recommendation.

  7. Routine programme guidance has been updated to include additional information about action to take when hexavalent vaccine is given when pentavalent should have been given.

  8. The routine and selective guidance documents have been revised to comply with accessibility guidelines.

  9. First published.

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