Etoricoxib: prescribing to patients with high blood pressure
Do not prescribe etoricoxib to patients whose blood pressure is persistently above 140/90 mmHg and inadequately controlled.
Article date: July 2008
The has completed a review of the benefits and risks of 90 mg etoricoxib (Arcoxiaâ–¼) in the treatment of rheumatoid arthritis and ankylosing spondylitis. The Agency바카라 사이트™s has concluded that etoricoxib바카라 사이트™s benefits outweigh the risks in the treatment of rheumatoid arthritis. Furthermore, the Committee recommended extension of the indication to include ankylosing spondylitis at a dose of 90 mg once a day.
However, the Committee recommended an update to the existing contraindication in patients with inadequately controlled hypertension to state that patients whose blood pressure is persistently above 140/90 mmHg and inadequately controlled must not receive etoricoxib. Furthermore, high blood pressure should be controlled before starting treatment, and should be monitored for 2 weeks after the start of treatment and regularly thereafter.
Advice for healthcare professionals includes:
- prescribe etoricoxib in accordance with the above updated product information
- monitor patients closely for any signs and symptoms of cardiovascular side-effects (eg, fluid retention, high blood pressure, shortness of breath, or chest pain)
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Article citation: Drug Safety Use July 2008; Vol 1, Issue 12: 10